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Showing 1–3 of 3 results
Advanced filters: Author: Maya Sangesland Clear advanced filters
  • There is currently no approved influenza vaccine for newborns, so development of such a vaccine is warranted. Here the authors show, using a African green monkey newborn model, that an adjuvanted nanoparticle vaccine containing the stem region of influenza hemagglutinin can induce robust IgG responses, with the functionality of the antibodies linked to viral clearance.

    • Kali F. Crofts
    • Beth C. Holbrook
    • Martha A. Alexander-Miller
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16
  • Antibodies play a crucial role in protection from influenza virus infection, but functional details, particularly in older adults, are incomplete. Here the authors show that NK cell-activating antibodies are associated with protection from influenza infection in vaccinated older adults.

    • Carolyn M. Boudreau
    • John S. Burke IV
    • Galit Alter
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11
  • Here, Li et al. perform a genome-wide CRISPR screen to identify host dependency factors for influenza A virus infection and show that the host mRNA cap methyltransferase CMTR1 is important for viral cap snatching and that it affects expression of antiviral genes.

    • Bo Li
    • Sara M. Clohisey
    • Nir Hacohen
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-18