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Showing 1–6 of 6 results
Advanced filters: Author: Maya Shelly Clear advanced filters

  • The molecular composition of the axon initial segment (AIS) is not well defined. Here, the authors used a ratiometric immunoproximity labeling strategy on fixed wild-type rat neurons to identify the AIS proteome, including the scaffolding protein SCRIB.

    • Wei Zhang
    • Yu Fu
    • Peng Zou
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • HLA peptidomic analysis identifies recurrent intracellular bacteria-derived peptides presented on HLA-I and HLA-II molecules in melanoma tumours, revealing how bacteria can modulate immune functions and responses to cancer therapies.

    • Shelly Kalaora
    • Adi Nagler
    • Yardena Samuels
    Research
    Nature
    Volume: 592, P: 138-143

  • Genome-wide analyses in over one million self-reported cases and controls identify genetic variants associated with stuttering and find genetic correlations with autism, depression and impaired musical rhythm, supporting a potential neurological basis for stuttering.

    • Hannah G. Polikowsky
    • Alyssa C. Scartozzi
    • Jennifer E. Below
    ResearchOpen Access
    Nature Genetics
    Volume: 57, P: 1835-1847

  • Early neural development is regulated by the neurotransmitter GABA acting through ionotropic GABAA receptors; however, the function of metabotropic GABAB receptors in this context is less clear. Here the authors show that GABABreceptors promote neuronal migration and maturation by activating cAMP signalling.

    • Guillaume Bony
    • Joanna Szczurkowska
    • Laura Cancedda
    Research
    Nature Communications
    Volume: 4, P: 1-15

  • In this Consensus Statement, the Treatment Response Measure for Systemic Lupus Erythematosus Consortium presents the initial outcomes of a project to develop a clinical outcome assessment that can contribute to the regulatory approval process for therapeutic agents via its incorporation in end points of clinical trials in systemic lupus erythematosus.

    • Kathryn Connelly
    • Laura E. Eades
    • Yulia Pincus
    Reviews
    Nature Reviews Rheumatology
    Volume: 19, P: 592-602