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Author Correction: A cell-free platform for the prenylation of natural products and application to cannabinoid production

Meaghan A. Valliere
Tyler P. Korman
James U. Bowie
Amendments and CorrectionsOpen Access24 May 2019
Nature Communications

Volume: 10, P: 1
A cell-free platform for the prenylation of natural products and application to cannabinoid production

Producing individual cannabinoids by metabolically engineered microbes has proven challenging. Here, the authors develop a cell-free enzymatic prenylating system to generate isoprenyl pyrophosphate substrates directly from glucose and produce both common and rare cannabinoids at >1 g/L.

Meaghan A. Valliere
Tyler P. Korman
James U. Bowie
ResearchOpen Access04 Feb 2019
Nature Communications

Volume: 10, P: 1-9
A bio-inspired cell-free system for cannabinoid production from inexpensive inputs

A cell-free system for cannabinoid production uses only low-cost inputs with 12 enzymes and can operate either aerobically or anaerobically, in addition to reducing ATP requirements by use of an engineered system for malonate-CoA biosynthesis.

Meaghan A. Valliere
Tyler P. Korman
James U. Bowie
Research24 Aug 2020
Nature Chemical Biology

Volume: 16, P: 1427-1433

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