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Showing 1–4 of 4 results
Advanced filters: Author: Megan M. Monsanto Clear advanced filters
  • Despite recent progress to advance cardiac cell-based therapy for patients, heart failure mortality rivals most cancers. Here, the authors describe an approach to control and pattern 3 distinct human cardiac cell populations to promote superior repair and regeneration after myocardial infarction.

    • Megan M. Monsanto
    • Bingyan J. Wang
    • Mark A. Sussman
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-20
  • The malaria parasite uses the methylerythritol phosphate (MEP) pathway to synthesize crucial isoprenoid metabolites. Here the authors identify and characterize a sugar phosphatase that regulates the MEP pathway by indirectly regulating the levels of isoprenoid precursors.

    • Ann M. Guggisberg
    • Jooyoung Park
    • Audrey R. Odom
    Research
    Nature Communications
    Volume: 5, P: 1-10
  • Philipp Simon, Massimo Iorizzo, Allen Van Deynze and colleagues report the high-quality assembly of the carrot genome, providing an important resource for crop improvement. They find a candidate gene that regulates carotenoid accumulation and gain further insights into asterid genome evolution, including characterization of two new polyploidization events.

    • Massimo Iorizzo
    • Shelby Ellison
    • Philipp Simon
    ResearchOpen Access
    Nature Genetics
    Volume: 48, P: 657-666
  • Broughton et al. report differences between rodent and large mammals with respect to ploidy of the cardiac interstitial cell population. These species-specific differences in ploidy of cardiac interstitial cells suggest potential challenges in extrapolating myocardial preclinical studies from rodent to large mammals.

    • Kathleen M. Broughton
    • Tiffany Khieu
    • Mark A. Sussman
    ResearchOpen Access
    Communications Biology
    Volume: 2, P: 1-14