A one-step preparation method of electrospun, synthetic scaffolds with controlled surface chemistry and functionality is reported. On addition of amphiphilic macromolecules, non-specific protein adsorption on the fibres’ surfaces is reduced, and by the further covalent attachment of certain peptide sequences to the fibres, specific bioactivation of the scaffold is achieved.
- Dirk Grafahrend
- Karl-Heinz Heffels
- Jürgen Groll
