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Showing 1–7 of 7 results
Advanced filters: Author: Melanie Clerc Clear advanced filters

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • In order to assess the extent by which microbial communities from multiple body sites are linked and related to disease susceptibility, Reyman and Clerc et al. combined 16S-based rRNA sequencing data from 112 healthy, term born infants, spanning three body sites (oral cavity, nasopharynx, gut) over the first six months of life. They demonstrate a strong association between network structure and species and susceptibility to respiratory tract infections, suggesting a crucial role of cross-niche microbial connections in respiratory health.

    • Marta Reyman
    • Melanie Clerc
    • Debby Bogaert
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-11

  • The causative agent of cholera, Vibrio cholerae, is commonly found in aquatic habitats, where it must defend itself against predatory protists such as amoebae. Here, Van der Henst et al. analyze the molecular mechanisms by which V. cholerae thrives within, and ultimately escapes from, aquatic amoebae.

    • Charles Van der Henst
    • Audrey Sophie Vanhove
    • Melanie Blokesch
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13