Meiotic recombination enables reciprocal exchange of genetic material between paternal and maternal homologous chromosomes. Here Luo et al.show that MEIOB, a novel meiosis-specific factor identified in a proteomics screen, forms complexes with RPA2 and SPATA22, and is required for meiotic recombination.
- Mengcheng Luo
- Fang Yang
- P. Jeremy Wang