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Showing 1–5 of 5 results
Advanced filters: Author: Meredith A. Redd Clear advanced filters

  • Measures of hyperglycaemia are risk factors for cardiovascular disease. Here the authors report that glycaemic variability is also a driver of cardiac vulnerability in diabetes, integrating population genetics, clinical data and experimental models to show how glucose fluctuations worsen heart injury and cardiovascular risk.

    • Yuanzhao Cao
    • Meredith A. Redd
    • Nathan J. Palpant
    ResearchOpen Access
    Nature Communications
    P: 1-14

  • Examining drivers of the latitudinal biodiversity gradient in a global database of local tree species richness, the authors show that co-limitation by multiple environmental and anthropogenic factors causes steeper increases in richness with latitude in tropical versus temperate and boreal zones.

    • Jingjing Liang
    • Javier G. P. Gamarra
    • Cang Hui
    Research
    Nature Ecology & Evolution
    Volume: 6, P: 1423-1437

  • Heart grafts need good vascularization to survive. Here, the authors engineer perfusable constructs of human embryonic stem cell-derived endothelial cells seeded in collagen matrix in patterned microchannels that form anastomosed vessels in vitro and have increased coronary vascular perfusion on transplantation in rats.

    • Meredith A. Redd
    • Nicole Zeinstra
    • Ying Zheng
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14

  • Sinclair et al. explore the contribution of chronic inflammation to cardiovascular symptoms associated with post-acute sequelae of SARS-CoV-2 infection (PASC-CVS). The authors identify trace levels of inflammatory cytokines in individuals with PASC-CVS that impair the function of cardiomyocytes derived from induced pluripotent stem cells.

    • Jane E. Sinclair
    • Courtney Vedelago
    • Kirsty R. Short
    ResearchOpen Access
    Nature Microbiology
    Volume: 9, P: 3135-3147