Nature Search

The intrinsic factor–vitamin B₁₂ receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein

Renata Kozyraki
John Fyfe
Søren K. Moestrup
Research01 Jun 1999
Nature Medicine

Volume: 5, P: 656-661
LGR signaling mediates muscle-adipose tissue crosstalk and protects against diet-induced insulin resistance

Obesity induces insulin resistance and impairs insulin signaling, causing diabetes. Here, the authors show that BMP and LGR signaling mediate communication between muscle, neuronal, and adipose tissues to enhance insulin signaling, identifying LGR as key in protecting against insulin resistance.

Olga Kubrak
Anne F. Jørgensen
Kim Rewitz
ResearchOpen Access20 Jul 2024
Nature Communications

Volume: 15, P: 1-22
Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum

Genome-wide analyses identify variants associated with infertility and reproductive hormone levels but find limited polygenic overlap between reproductive hormone levels and infertility at the population level.

Samvida S. Venkatesh
Laura B. L. Wittemans
Cecilia M. Lindgren
ResearchOpen Access14 Apr 2025
Nature Genetics

Volume: 57, P: 1107-1118
Protein-responsive gut hormone tachykinin directs food choice and impacts lifespan

The gut hormone tachykinin (Tk) is found to be regulated by protein intake in flies and mice. In flies, Tk is shown to impact food choices, sleep and lifespan.

Nadja Ahrentløv
Olga Kubrak
Kim Rewitz
ResearchOpen Access14 Apr 2025
Nature Metabolism

Volume: 7, P: 1223-1245
Gene-based burden tests of rare germline variants identify six cancer susceptibility genes

Burden testing in three large European ancestry cohorts identifies new risk genes for a number of common cancer types, including pan-cancer protective variants in AURKB and breast cancer protective variants in PPP1R15A.

Erna V. Ivarsdottir
Julius Gudmundsson
Kari Stefansson
Research29 Oct 2024
Nature Genetics

Volume: 56, P: 2422-2433
Experience exceeds awareness of anthropogenic climate change in Greenland

Greenland is at the heart of climate research, yet the related perceptions of Greenland’s Indigenous population have long been overlooked. Findings based on two nationally representative surveys reveal a large gap between the scientific consensus and Kalaallit views.

Kelton Minor
Manumina Lund Jensen
Minik T. Rosing
ResearchOpen Access26 Jun 2023
Nature Climate Change

Volume: 13, P: 661-670
A microbial supply chain for production of the anti-cancer drug vinblastine

De novo microbial biosynthesis of vindoline and catharanthine using a highly engineered yeast and in vitro chemical coupling to vinblastine is carried out, positioning yeast as a scalable platform to produce many monoterpene indole alkaloids.

Jie Zhang
Lea G. Hansen
Jay D. Keasling
ResearchOpen Access31 Aug 2022
Nature

Volume: 609, P: 341-347
Identification of the haemoglobin scavenger receptor

Mette Kristiansen
Jonas H. Graversen
Søren K. Moestrup
Research11 Jan 2001
Nature

Volume: 409, P: 198-201
The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress

Intestinal nutrient-sensing is important in metabolic control. Here the authors show that the gut-derived hormone Allatostatin C, a somatostatin homolog in fruit flies, links enteric nutrient sensing to behavioral and metabolic adaptations that maintain energetic homeostasis in Drosophila melanogaster.

Olga Kubrak
Takashi Koyama
Kim Rewitz
ResearchOpen Access04 Feb 2022
Nature Communications

Volume: 13, P: 1-17

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