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Showing 1–3 of 3 results

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Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

A diverse collection of potent neutralizing antibodies against the SARS-CoV-2 spike protein have been isolated from five patients with severe COVID-19 and high serum neutralization titres.

Lihong Liu
Pengfei Wang
David D. Ho
Research22 Jul 2020
Nature

Volume: 584, P: 450-456
Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs

The challenge of accurate particle picking in cryo-EM analysis is addressed with Topaz, a neural-network-based algorithm that shows advantages over other tools, especially in picking unusually shaped particles.

Tristan Bepler
Andrew Morin
Bonnie Berger
Research07 Oct 2019
Nature Methods

Volume: 16, P: 1153-1160
Visualization of clustered protocadherin neuronal self-recognition complexes

Clustered protocadherin ectodomains spontaneously assemble to form a zipper-like lattice of alternating cis and trans interactions at membrane contact sites, which probably represents their mode of function in neuronal self-recognition.

Julia Brasch
Kerry M. Goodman
Lawrence Shapiro
Research10 Apr 2019
Nature

Volume: 569, P: 280-283