Mendelsohn et al. evaluated in a prospective multicentre validation study whether host-blood transcriptomic tuberculosis (TB) signatures could be used to find active cases of TB. Whilst most of the signatures met WHO Target Product Profile criteria for a triage test to diagnose symptomatic TB; most signatures did not meet the criteria for asymptomatic TB.
- Simon C. Mendelsohn
- Stanley Kimbung Mbandi
- Thomas J. Scriba
