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Showing 1–46 of 46 results
Advanced filters: Author: Michael Attwaters Clear advanced filters

  • A recent study identifies a compound that sensitizes fungal pathogens to the antifungal drug caspofungin.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Microbiology
    P: 1

  • Bats use echolocation to navigate long distances without relying on other sensory information.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 26, P: 64

  • Tan et al. identify a population of leptin-responsive neurons that regulate food intake and body weight.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 26, P: 2

  • A study in Nature describes how single-cell expression data can be used to understand gene regulatory landscapes in bacteria.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 25, P: 234

  • Guhlin et al. sequenced the genomes of almost the entire extant population of the critically-endangered kākāpō, revealing genetic variants for fitness-related traits that can inform conservation strategies.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 736

  • A new study in Nature Genetics describes how changes in the levels of transcription factors can affect normal-range phenotypic variation and disease.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 416

  • A study in Nature identified the presumed owner or maker of a 20,000-year-old pendant.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 416

  • Two recent studies published in Nature Biotechnology describe the engineering of circularized guide RNAs, which allow for programmable RNA base editing in vivo, with vastly improved editing efficiency and durability.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 23, P: 196-197

  • A new study in Nature uses genetic information from a single blood sample to monitor pregnancy progression and to identify women at risk of pre-eclampsia before the onset of symptoms.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 23, P: 136

  • In this study, the authors investigate the mechanistic basis of alternative telomere lengthening, a process that certain cancer cells use to overcome telomere shortening.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Cancer
    Volume: 23, P: 192

  • An article in Environmental Research Letters models the impact of climate change on future trends in hazardous driving conditions along two important transport systems within the Arctic–Boreal region.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Earth & Environment
    Volume: 4, P: 140

  • Hao et al. present a workflow to integrate single-cell datasets of diverse modalities using a multi-omic dataset as a molecular bridge.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 488

  • A recent study finds that an enzyme expressed by gut bacteria can inactivate anti-cancer fluoropyrimidine drugs, reducing drug efficacy and bioavailability in mice.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Microbiology
    Volume: 20, P: 704

  • A new study identified two distinct lineages of monkeypox virus (MPXV) in the United States with evidence of genome editing by host apolipoprotein B editing complex (APOBEC3) cytosine deaminase, which might be accelerating MPXV evolution.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Microbiology
    Volume: 21, P: 4

  • New research has identified a novel, de novo mutation in the TLR7 gene that increases the affinity of TLR7 for guanosine, leading to TLR7 overactivation and child-onset systemic lupus erthematosus.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Rheumatology
    Volume: 18, P: 365

  • Arevalo et al. have developed a nucleoside-modified mRNA-lipid nanoparticle vaccine encoding separate haemagglutinin antigens from all known influenza virus subtypes.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Microbiology
    Volume: 21, P: 67

  • A recent study used a zebrafish model to show that the microbiota promotes social behaviour by stimulating microglial pruning of brain circuits during early neurodevelopment.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Microbiology
    Volume: 21, P: 4

  • Meyer et al. show that Toxoplasma gondii infection influences wolf behaviour in the wild, increasing risk-taking behaviours such as dispersing from a pack and becoming a pack leader.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Microbiology
    Volume: 21, P: 67

  • In this study, a multinational and multidisciplinary panel of experts provides actionable recommendations for policy makers to end the COVID-19 pandemic.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Microbiology
    Volume: 21, P: 3

  • Kalkavan et al. show how drug-tolerant persister cells evade apoptosis by release of sublethal cytochrome c and activation of the integrated stress response.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Molecular Cell Biology
    Volume: 23, P: 697

  • New research demonstrates that a hydrogel-based miRNA delivery system might have therapeutic potential to treat osteoarthritis by targeting chondrocyte senescence.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Rheumatology
    Volume: 18, P: 305

  • Wu et al. provide mechanistic insight into how the plant symbiotic fungus Metarhizium robertsii can reduce mercury accumulation in soil.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Microbiology
    Volume: 21, P: 67

  • Preclinical research suggests the focal adhesion protein kindlin-2 protects against intervertebral disc degeneration.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Rheumatology
    Volume: 18, P: 125

  • A machine learning approach has been used to identify three distinct osteoarthritis endotypes based on biochemical markers related to joint tissue processes.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Rheumatology
    Volume: 18, P: 246

  • Four papers in Nature describe how ancient European migration patterns have shaped the modern human genome.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 25, P: 162

  • Three papers in Nature report on the largest open-access plasma proteomics dataset to date, a valuable resource for understanding human disease and the identification of drug targets.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 806

  • Two studies published in Nature investigate the genetic mechanisms of sex bias in cancers and implicate Y chromosome genes in contributing to the aggressiveness of bladder cancer and colorectal cancer in men.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 661

  • Breda et al. developed a method for gene editing bone marrow cells in vivo, circumventing the need for toxic conditioning regimens such as chemotherapy or radiation.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 662

  • Morris et al. present an integrated multi-omic workflow to identify target genes of noncoding variants for blood trait loci.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 489

  • Zeng et al. introduce RIBOmap, a three-dimensional in situ imaging technique that enables the mapping of mRNAs undergoing translation.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 587

  • In five new studies, the Human Pangenome Reference Consortium reports the generation and initial characterization of a draft human pangenome.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 585

  • In six new studies published in Science, the Telomere-to-Telomere (T2T) Consortium reports the assembly and initial characterization of the final, previously unresolved 8% of the human genome.

    • Michael Attwaters
    Research Highlights
    Nature Reviews Genetics
    Volume: 23, P: 321