Previous work has suggested that the scaffolding protein ankyrin G is essential for the clustering of Na+ channels at the nodes of Ranvier. However, in this study, the authors show that, in the absence of ankyrin G, the complex of ankyrin R and βI spectrin can mediate Na+ channel clustering at the nodes.
- Tammy Szu-Yu Ho
- Daniel R Zollinger
- Matthew N Rasband
