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Showing 101–141 of 141 results

Advanced filters: Author: Michael Horowitz Clear advanced filters

Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting

Eli Sprecher, Kathleen Green and colleagues show that biallelic mutations in DSG1 cause a syndrome featuring severe dermatitis, multiple allergies and metabolic wasting. The mutations abolish expression of desmoglein 1, resulting in loss of cell adhesion accompanied by increased expression of several allergy-related cytokines.

Liat Samuelov
Ofer Sarig
Eli Sprecher
Research25 Aug 2013
Nature Genetics

Volume: 45, P: 1244-1248
Elevated serum SDMA and ADMA at hospital admission predict in-hospital mortality of COVID-19 patients

Juliane Hannemann
Paul Balfanz
Rainer Böger
ResearchOpen Access10 May 2021
Scientific Reports

Volume: 11, P: 1-12
Comparison of first-line and second-line terlipressin versus sole norepinephrine in fulminant ovine septic shock

Tim G. Kampmeier
Philip H. Arnemann
Christian Ertmer
ResearchOpen Access08 May 2018
Scientific Reports

Volume: 8, P: 1-11
Climate stability and societal decline on the margins of the Byzantine empire in the Negev Desert

Petra Vaiglova
Gideon Hartman
Guy Bar-Oz
ResearchOpen Access30 Jan 2020
Scientific Reports

Volume: 10, P: 1-13
Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network

Geoffrey S. Ginsburg
Larisa H. Cavallari
Sara Van Driest
Research29 Mar 2021
Genetics in Medicine

Volume: 23, P: 1185-1191
Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing

Piwi protein Miwi is shown to be a small RNA-guided RNase in mice; disrupting the catalytic activity of Miwi results in increased accumulation of LINE1 retrotransposon transcripts and male infertility.

Michael Reuter
Philipp Berninger
Ramesh S. Pillai
Research27 Nov 2011
Nature

Volume: 480, P: 264-267
Do Preclinical Findings of Methamphetamine-Induced Motor Abnormalities Translate to an Observable Clinical Phenotype?

Michael P Caligiuri
Casey Buitenhuys
Reviews10 Aug 2005
Neuropsychopharmacology

Volume: 30, P: 2125-2134
Charge density wave quantum critical point with strong enhancement of superconductivity

An experimental study of the rare-earth intermetallic system LuPt₂In reveals a strong enhancement of superconductivity near the charge density wave quantum critical point. This represents an unusual counter-example to cuprates, in which superconductivity and charge density waves tend to compete.

Thomas Gruner
Dongjin Jang
Christoph Geibel
Research10 Jul 2017
Nature Physics

Volume: 13, P: 967-972
Risk of thrombotic events after respiratory infection requiring hospitalization

Nathaniel R. Smilowitz
Varun Subashchandran
Jeffrey S. Berger
ResearchOpen Access18 Feb 2021
Scientific Reports

Volume: 11, P: 1-9
Effect of gender on the acute effects of whey protein ingestion on energy intake, appetite, gastric emptying and gut hormone responses in healthy young adults

Caroline Giezenaar
Natalie D Luscombe-Marsh
Stijn Soenen
ResearchOpen Access13 Jul 2018
Nutrition & Diabetes

Volume: 8, P: 1-12
20q gain associates with immortalization: 20q13.2 amplification correlates with genome instability in human papillomavirus 16 E7 transformed human uroepithelial cells

Elena Savelieva
Cassandra D Belair
Catherine A Reznikoff
Research06 Feb 1997
Oncogene

Volume: 14, P: 551-560
Wintertime vitamin D insufficiency is common in young Canadian women, and their vitamin D intake does not prevent it

R Vieth
DE Cole
LA Rubin
Research11 Dec 2001
European Journal of Clinical Nutrition

Volume: 55, P: 1091-1097
Gastric emptying of a glucose drink is predictive of the glycaemic response to oral glucose and mixed meals, but unrelated to antecedent glycaemic control, in type 2 diabetes

Chunjie Xiang
Yixuan Sun
Tongzhi Wu
ResearchOpen Access08 Apr 2024
Nutrition & Diabetes

Volume: 14, P: 1-7
Pan-cancer patterns of somatic copy number alteration

Rameen Beroukhim and colleagues analyzed somatic structural alterations in 12 tumor types. Whole-genome doubling was found in over a third of all cancers, associated with TP53 mutation. Fifteen new significantly mutated candidate driver genes were found associated with recurrently amplified or deleted regions.

Travis I Zack
Steven E Schumacher
Rameen Beroukhim
ResearchOpen Access26 Sept 2013
Nature Genetics

Volume: 45, P: 1134-1140
Metabolites and diabetes remission after weight loss

Lydia Coulter Kwee
Olga Ilkayeva
Blandine Laferrère
ResearchOpen Access24 Feb 2021
Nutrition & Diabetes

Volume: 11, P: 1-13
Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21^WAF1/CIP1 during NGF-mediated neuronal differentiation

Nathalie Billon
Didier Carlisi
Brian B Rudkin
Research20 May 1999
Oncogene

Volume: 18, P: 2872-2882
Genome-wide association identifies novel ROP risk loci in a multiethnic cohort

A GWAS in a multi-ethnic cohort identifies a novel association between the GLI3 SNP rs2058019 and retinopathy of prematurity (ROP) severity, which was confirmed as relevant to preretinal neovascular disease and human ocular gene expression.

Xiaohui Li
Leah A. Owen
Cristina Montero-Mendoza
ResearchOpen Access17 Jan 2024
Communications Biology

Volume: 7, P: 1-13
ATR and CDK4/6 inhibition target the growth of methotrexate-resistant choriocarcinoma

Marina Georgiou
Panagiota Ntavelou
Olivier E. Pardo
ResearchOpen Access18 Mar 2022
Oncogene

Volume: 41, P: 2540-2554
Effects of intragastric administration of L-tryptophan on the glycaemic response to a nutrient drink in men with type 2 diabetes — impacts on gastric emptying, glucoregulatory hormones and glucose absorption

Maryam Hajishafiee
Rachel A. Elovaris
Christine Feinle-Bisset
ResearchOpen Access05 Jan 2021
Nutrition & Diabetes

Volume: 11, P: 1-9
Clinical correlates and prognostic impact of neurologic disorders in Takotsubo syndrome

Victoria L. Cammann
Jan F. Scheitz
Thomas F. Lüscher
ResearchOpen Access07 Dec 2021
Scientific Reports

Volume: 11, P: 1-14
Historical total ozone radiative forcing derived from CMIP6 simulations

Ragnhild Bieltvedt Skeie
Gunnar Myhre
Tongwen Wu
ResearchOpen Access17 Aug 2020
npj Climate and Atmospheric Science

Volume: 3, P: 1-10
Acute effects of whey protein on energy intake, appetite and gastric emptying in younger and older, obese men

Avneet Oberoi
Caroline Giezenaar
Stijn Soenen
ResearchOpen Access02 Oct 2020
Nutrition & Diabetes

Volume: 10, P: 1-9
In Vivo Water Dynamics in Shewanella oneidensis Bacteria at High Pressure

Fabrizia Foglia
Rachael Hazael
Paul F. McMillan
ResearchOpen Access18 Jun 2019
Scientific Reports

Volume: 9, P: 1-11
Correction: ATR and CDK4/6 inhibition target the growth of methotrexate-resistant choriocarcinoma

Marina Georgiou
Panagiota Ntavelou
Olivier E. Pardo
Amendments and CorrectionsOpen Access30 May 2022
Oncogene

Volume: 41, P: 3510
Severe clinical relapse in an immunocompromised host with persistent SARS-CoV-2 infection

Philipp A. Reuken
Andreas Stallmach
Michael Bauer
CorrespondenceOpen Access19 Feb 2021
Leukemia

Volume: 35, P: 920-923
The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant

Inge M. M. Lakeman
Alexandra J. van den Broek
Marjanka K. Schmidt
ResearchOpen Access10 Jun 2021
Genetics in Medicine

Volume: 23, P: 1726-1737
Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2

Denise G. O’Mahony
Susan J. Ramus
Elizabeth Santana dos Santos
ResearchOpen Access19 Apr 2023
British Journal of Cancer

Volume: 128, P: 2283-2294
Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint

Jung-Sik Kim
Farzaneh Pirnia
Jane B Trepel
Research07 Dec 2000
Oncogene

Volume: 19, P: 6082-6090
UCN-01-mediated G1 arrest in normal but not tumor breast cells is pRb-dependent and p53-independent

Xiaomei Chen
Michael Lowe
Khandan Keyomarsi
Research08 Oct 1999
Oncogene

Volume: 18, P: 5691-5702
Glycaemic variability is associated with all-cause mortality in COVID-19 patients with ARDS, a retrospective subcohort study

Bojan Hartmann
Marlo Verket
Dirk Müller-Wieland
ResearchOpen Access14 Jun 2022
Scientific Reports

Volume: 12, P: 1-10
Time-resolved small-angle neutron scattering as a probe for the dynamics of lipid exchange between human lipoproteins and naturally derived membranes

Selma Maric
Tania Kjellerup Lind
Marité Cárdenas
ResearchOpen Access20 May 2019
Scientific Reports

Volume: 9, P: 1-14
Structural basis for activation of plasma-membrane Ca²⁺-ATPase by calmodulin

Julius Nitsche et al. demonstrate that binding of two calmodulin molecules displaces the regulatory domain of the plasma-membrane Ca²⁺-ATPase ACA8 to fully activate this Ca²⁺ pump by relieving the autoinhibition. This work provides structural evidence for the previously proposed bimodular activation mechanism.

Julius Nitsche
Inokentijs Josts
Henning Tidow
ResearchOpen Access26 Nov 2018
Communications Biology

Volume: 1, P: 1-10
Thermal activation of ‘allosteric-like’ large-scale motions in a eukaryotic Lactate Dehydrogenase

Marina Katava
Marco Maccarini
Fabio Sterpone
ResearchOpen Access23 Jan 2017
Scientific Reports

Volume: 7, P: 1-12
Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome

Henry Richard Johnston
Yi-Juan Hu
Maria Yazdanbakhsh
ResearchOpen Access21 Apr 2017
Scientific Reports

Volume: 7, P: 1-9
Difficult lives explain depression better than broken brains

Joanna Moncrieff
Ruth E. Cooper
Mark A. Horowitz
Correspondence19 Feb 2024
Molecular Psychiatry

Volume: 29, P: 206-209
Donor body mass index does not predict graft versus host disease following hematopoietic cell transplantation

Lucie M. Turcotte
Tao Wang
Michael R. Verneris
Correspondence30 Jan 2018
Bone Marrow Transplantation

Volume: 53, P: 932-937
Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1)

Rasa Sukackaite
Daniela Cornacchia
Sara B. C. Buonomo
ResearchOpen Access18 May 2017
Scientific Reports

Volume: 7, P: 1-10
The serotonin hypothesis of depression: both long discarded and still supported?

Joanna Moncrieff
Ruth E. Cooper
Mark A. Horowitz
Correspondence16 Jun 2023
Molecular Psychiatry

Volume: 28, P: 3160-3163
Assessment of p53 gene transfer and biological activities in a clinical study of adenovirus-p53 gene therapy for recurrent ovarian cancer

Shu Fen Wen
Vikas Mahavni
Richard Buller
Research14 Mar 2003
Cancer Gene Therapy

Volume: 10, P: 224-238
The serotonin theory of depression: a systematic umbrella review of the evidence

Joanna Moncrieff
Ruth E. Cooper
Mark A. Horowitz
ReviewsOpen Access20 Jul 2022
Molecular Psychiatry

Volume: 28, P: 3243-3256
Vascular tumors have increased p70 S6-kinase activation and are inhibited by topical rapamycin

Wa Du
Damien Gerald
Thuy L Phung
Research12 Aug 2013
Laboratory Investigation

Volume: 93, P: 1115-1127

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