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Showing 1–4 of 4 results

Advanced filters: Author: Michael J. Gutbrod Clear advanced filters

A synthetic transcription platform for programmable gene expression in mammalian cells

Precise and scalable regulation of gene expression in mammalian cells is challenging. Here, the authors created a highly tunable CRISPR-based synthetic transcription system for programmable control of mammalian gene expression and cellular activity.

William C. W. Chen
Leonid Gaidukov
Timothy K. Lu
ResearchOpen Access18 Oct 2022
Nature Communications

Volume: 13, P: 1-16
Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation

Michael P. Schön
Thomas Krahn
W.-Henning Boehncke
Research01 Apr 2002
Nature Medicine

Volume: 8, P: 366-372
Conserved chromosomal functions of RNA interference

RNA interference (RNAi) effector proteins have highly conserved roles in chromosome function. This Review traces the evolutionary history of RNAi components and discusses their lesser-known roles in regulating chromosome segregation, gene dosage and DNA damage resolution, from unicellular eukaryotes to mammals.

Michael J. Gutbrod
Robert A. Martienssen
Reviews12 Feb 2020
Nature Reviews Genetics

Volume: 21, P: 311-331
Mode of action of fluopyram in plant-parasitic nematodes

A. Sylvia S. Schleker
Marc Rist
Florian M. W. Grundler
ResearchOpen Access13 Jul 2022
Scientific Reports

Volume: 12, P: 1-14