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Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells

Treatment of primary glioblastoma cell lines with epigenetic therapy reactivates transposable elements (TEs). TE-derived transcripts can produce human leukocyte antigen class I-presented antigens, which could potentially be therapeutically targeted.

H. Josh Jang
Nakul M. Shah
Ting Wang
Research02 Sept 2024
Nature Genetics

Volume: 56, P: 1903-1913
Six Versus Twelve Months Clopidogrel Therapy After Drug-Eluting Stenting in Patients With Acute Coronary Syndrome: An ISAR-SAFE Study Subgroup Analysis

Raphaela Lohaus
Jonathan Michel
Stefanie Schulz-Schüpke
ResearchOpen Access14 Sept 2016
Scientific Reports

Volume: 6, P: 1-9
Ketamine for Social Anxiety Disorder: A Randomized, Placebo-Controlled Crossover Trial

Jerome H Taylor
Angeli Landeros-Weisenberger
Michael H Bloch
Research29 Aug 2017
Neuropsychopharmacology

Volume: 43, P: 325-333