Serotonin is a key intercellular signalling molecule with well-known functions in the gastrointestinal tract, particularly for motility. This Review explores the non-conventional roles of gut-derived serotonin in the gut and other peripheral tissues, including during gastrointestinal inflammation, haematopoiesis, metabolic homeostasis and bone remodelling.
- Stephanie N. Spohn
- Gary M. Mawe