Nature Search

Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor–type integrins inhibits retinal neovascularization

Hans-Peter Hammes
Michael Brownlee
Klaus T. Preissner
Research01 May 1996
Nature Medicine

Volume: 2, P: 529-533
Fair human-centric image dataset for ethical AI benchmarking

The Fair Human-Centric Image Benchmark (FHIBE, pronounced ‘Feebee’)—an image dataset that implements best practices for consent, privacy, compensation, safety, diversity and utility—can be used responsibly as a fairness evaluation dataset for many human-centric computer vision applications.

Alice Xiang
Jerone T. A. Andrews
Michael Spranger
ResearchOpen Access05 Nov 2025
Nature

Volume: 648, P: 97-108
Semiotic Dynamics Solves the Symbol Grounding Problem

Luc Steels
Martin Loetzsch
Michael Spranger
ResearchOpen Access17 Oct 2007
Nature Precedings

P: 1
PAK4 inhibition improves PD-1 blockade immunotherapy

Ribas and colleagues report that inhibition of PAK4 improves response to anti-PD-1 immunotherapy by reducing Wnt pathway activation and increasing tumor infiltration by T cells.

Gabriel Abril-Rodriguez
Davis Y. Torrejon
Antoni Ribas
Research09 Dec 2019
Nature Cancer

Volume: 1, P: 46-58
Exclusive paternal origin of new mutations in Apert syndrome

Dominique M. Moloney
Sarah R Slaney
Andrew O.M. Wilkie
Research01 May 1996
Nature Genetics

Volume: 13, P: 48-53
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

The MAGIC investigators report results of a large genome-wide association study meta-analysis to identify common variants influencing fasting glucose homeostasis. They further show that several of the newly discovered loci influencing glycemic traits are also associated with risk of type 2 diabetes.

Josée Dupuis
Claudia Langenberg
Inês Barroso
Research17 Jan 2010
Nature Genetics

Volume: 42, P: 105-116
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC

Merbl and colleagues demonstrate that high expression of the proteasome regulator PSME4 is associated with immune-cold lung tumors and reduced antitumor immune responses, by functioning to modulate the protein degradome and antigen diversity.

Aaron Javitt
Merav D. Shmueli
Yifat Merbl
Research22 May 2023
Nature Cancer

Volume: 4, P: 629-647
Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes

Sengupta et al. show that the mesenchymal cell state in neuroblastoma is associated with heightened immunogenicity and anti-tumor immune responses compared with the adrenergic state, which is linked to sensitivity to immunotherapy in preclinical models.

Satyaki Sengupta
Sanjukta Das
Rani E. George
Research22 Sept 2022
Nature Cancer

Volume: 3, P: 1228-1246
Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway

Recent work found that overexpression of short hairpin RNAs in cells could lead to mortality in mice, this was attributed to interference with the cellular machinery that makes miRNAs. This raised the issue of whether RNA interference-mediated silencing would be therapeutically possible. This paper shows that small interfering RNAs can be systemically administered and effectively suppress gene expression without compromising the activity of various liver miRNAs.

Matthias John
Rainer Constien
David Bumcrot
Research26 Sept 2007
Nature

Volume: 449, P: 745-747
Recovery of Cardiovascular Function in Newborn Lambs after Thoracotomy

Daniel Sidi
Jaap R G Kuipers
Abraham M Rudolph
Research01 Sept 1982
Pediatric Research

Volume: 16, P: 705-710
Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Josée Dupuis
Claudia Langenberg
Inês Barroso
Amendments and Corrections01 May 2010
Nature Genetics

Volume: 42, P: 464
Outracing champion Gran Turismo drivers with deep reinforcement learning

Using the game Gran Turismo, an agent was trained with a combination of deep reinforcement learning algorithms and specialized training scenarios, demonstrating success against championship-level human racers.

Peter R. Wurman
Samuel Barrett
Hiroaki Kitano
Research09 Feb 2022
Nature

Volume: 602, P: 223-228
Stickler syndrome: Correlation between vitreoretinal phenotypes and linkage to COL 2A1

Martin P Snead
Stewart J Payne
John D Scott
Research01 Nov 1994
Eye

Volume: 8, P: 609-614
Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis

Victor L. Ruiz-Perez
Susan E. Ide
Judith Goodship
Research01 Mar 2000
Nature Genetics

Volume: 24, P: 283-286
Preselection of cases through expert clinical and radiological review significantly increases mutation detection rate in multiple epiphyseal dysplasia

Andreas Zankl
Gail C Jackson
Michael D Briggs
Research29 Nov 2006
European Journal of Human Genetics

Volume: 15, P: 150-154
Dietary Fat Intake Modulates Effects of a Frequent ACE Gene Variant on Glucose Tolerance with association to Type 2 Diabetes

Rita Schüler
Martin A. Osterhoff
Andreas F. H. Pfeiffer
ResearchOpen Access23 Aug 2017
Scientific Reports

Volume: 7, P: 1-7
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis

Here Ramanan and colleagues provide an analysis of mammary T cells during late pregnancy and lactation. This revealed an increase in intraepithelial lymphocytes in the lactating mammary gland, which was driven by thymic and intestinal inputs and was sensitive to changes in the microbiota

Abigail Jaquish
Eleni Phung
Deepshika Ramanan
Research29 Jul 2025
Nature Immunology

Volume: 26, P: 1411-1422
Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy

Cytotoxic chemotherapy rarely generates durable anti-tumor immune responses. Here the authors show that tumor microenvironment-derived IL-6 promotes resistance to doxorubicin by suppressing CD8 T cell anti-tumor immune responses in a preclinical model of B-cell acute lymphoblastic leukemia.

Eric H. Bent
Luis R. Millán-Barea
Michael T. Hemann
ResearchOpen Access28 Oct 2021
Nature Communications

Volume: 12, P: 1-13
Changes in aqueous and vitreous inflammatory cytokine levels in proliferative diabetic retinopathy: a systematic review and meta-analysis

Ryan H. Mason
Samuel A. Minaker
Rajeev H. Muni
Reviews07 Jun 2022
Eye

P: 1-51
Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents

Some adolescents seek novelty, but it is unknown whether the brain circuits underlying this behaviour can be used to predict later, problematic behaviour. Here, authors show that diminished ventral striatal and prefrontal activity in response to anticipated rewards at age 14 in these individuals predicts problematic drug use at age 16.

Christian Büchel
Jan Peters
Veronika Ziesch
ResearchOpen Access21 Feb 2017
Nature Communications

Volume: 8, P: 1-11
CONTROLLED CARDIAC REOXYGENATION REDUCES NITRIC OXIDE (NO) PRODUCTION AND OXIDANT INJURY OP HYPOXEMIC INFANT HEARTS

Michael P Sherman
Gerald D Buckberg
Louis J Ignarro
Research01 Feb 1994
Pediatric Research

Volume: 35, P: 260
A novel intermediate mucolipidosis II/IIIαβ caused by GNPTAB mutation in the cytosolic N-terminal domain

Jules G Leroy
David Sillence
Sara S Cathey
Research18 Sept 2013
European Journal of Human Genetics

Volume: 22, P: 594-601
FlavorGraph: a large-scale food-chemical graph for generating food representations and recommending food pairings

Donghyeon Park
Keonwoo Kim
Jaewoo Kang
ResearchOpen Access13 Jan 2021
Scientific Reports

Volume: 11, P: 1-13
Hypoxia and exercise interactions on skeletal muscle insulin sensitivity in obese subjects with metabolic syndrome: results of a randomized controlled trial

Knut Mai
Lars Klug
Friedrich C. Luft
Research09 Dec 2019
International Journal of Obesity

Volume: 44, P: 1119-1128
The clinical-phenotype continuum in DYNC1H1-related disorders—genomic profiling and proposal for a novel classification

Lena-Luise Becker
Hormos Salimi Dafsari
Sebahattin Cirak
ResearchOpen Access12 Aug 2020
Journal of Human Genetics

Volume: 65, P: 1003-1017
Linked patterns of biological and environmental covariation with brain structure in adolescence: a population-based longitudinal study

Amirhossein Modabbernia
Abraham Reichenberg
Sophia Frangou
ResearchOpen Access22 May 2020
Molecular Psychiatry

Volume: 26, P: 4905-4918
COMP mutation screening as an aid for the clinical diagnosis and counselling of patients with a suspected diagnosis of pseudoachondroplasia or multiple epiphyseal dysplasia

Jason Kennedy
Gail Jackson
Michael D Briggs
Research09 Mar 2005
European Journal of Human Genetics

Volume: 13, P: 547-555
Legal and ethical consequences of international biobanking from a national perspective: the German BMB-EUCoop project

Jürgen W Goebel
Thomas Pickardt
Michael Krawczak
Reviews02 Dec 2009
European Journal of Human Genetics

Volume: 18, P: 522-525
Peer victimization and its impact on adolescent brain development and psychopathology

Erin Burke Quinlan
Edward D. Barker
Gunter Schumann
Research12 Dec 2018
Molecular Psychiatry

Volume: 25, P: 3066-3076
The IMAGEN study: a decade of imaging genetics in adolescents

Lea Mascarell Maričić
Henrik Walter
Amir Tahmasebi
ReviewsOpen Access29 Jun 2020
Molecular Psychiatry

Volume: 25, P: 2648-2671
DRD2/ANKK1 Polymorphism Modulates the Effect of Ventral Striatal Activation on Working Memory Performance

Charlotte Nymberg
Tobias Banaschewski
J Rogers
Research09 Apr 2014
Neuropsychopharmacology

Volume: 39, P: 2357-2365

Search

Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor–type integrins inhibits retinal neovascularization

Fair human-centric image dataset for ethical AI benchmarking

Semiotic Dynamics Solves the Symbol Grounding Problem

PAK4 inhibition improves PD-1 blockade immunotherapy

Exclusive paternal origin of new mutations in Apert syndrome

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC

Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes

Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway

Recovery of Cardiovascular Function in Newborn Lambs after Thoracotomy

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Outracing champion Gran Turismo drivers with deep reinforcement learning

Stickler syndrome: Correlation between vitreoretinal phenotypes and linkage to COL 2A1

Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis

Preselection of cases through expert clinical and radiological review significantly increases mutation detection rate in multiple epiphyseal dysplasia

Dietary Fat Intake Modulates Effects of a Frequent ACE Gene Variant on Glucose Tolerance with association to Type 2 Diabetes

Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis

Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy

Changes in aqueous and vitreous inflammatory cytokine levels in proliferative diabetic retinopathy: a systematic review and meta-analysis

Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents

CONTROLLED CARDIAC REOXYGENATION REDUCES NITRIC OXIDE (NO) PRODUCTION AND OXIDANT INJURY OP HYPOXEMIC INFANT HEARTS

A novel intermediate mucolipidosis II/IIIαβ caused by GNPTAB mutation in the cytosolic N-terminal domain

FlavorGraph: a large-scale food-chemical graph for generating food representations and recommending food pairings

Hypoxia and exercise interactions on skeletal muscle insulin sensitivity in obese subjects with metabolic syndrome: results of a randomized controlled trial

The clinical-phenotype continuum in DYNC1H1-related disorders—genomic profiling and proposal for a novel classification

Linked patterns of biological and environmental covariation with brain structure in adolescence: a population-based longitudinal study

COMP mutation screening as an aid for the clinical diagnosis and counselling of patients with a suspected diagnosis of pseudoachondroplasia or multiple epiphyseal dysplasia

Legal and ethical consequences of international biobanking from a national perspective: the German BMB-EUCoop project

Peer victimization and its impact on adolescent brain development and psychopathology

The IMAGEN study: a decade of imaging genetics in adolescents

DRD2/ANKK1 Polymorphism Modulates the Effect of Ventral Striatal Activation on Working Memory Performance

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