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Showing 1–3 of 3 results
Advanced filters: Author: Michelle Bagby Clear advanced filters

  • The three-dimensional structure of the N-terminal domain of an archaeal TFIIB, which has high sequence homology with eucaryal analogues, is strikingly similar to that of the C-terminal zinc ribbon of the eucaryal transcription elongation factor TFIIS.

    • Wenlian Zhu
    • Qiandong Zeng
    • Robert A. Scott
    Correspondence
    Nature Structural Biology
    Volume: 3, P: 122-124

  • Here, the authors report a large-scale comparative analysis of <30,000 Diversity-Generating Retroelements (DGRs) across ~9000 metagenomes (representing diverse taxa and biomes), to identify patterns in terms of prevalence and activity. Combined with examination of longitudinal data on <100 metagenomes part of time series, they demonstrate that DGRs are broadly and consistently active, implying an important role in microbiota ecology and evolution.

    • Simon Roux
    • Blair G. Paul
    • Emiley A. Eloe-Fadrosh
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12