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Advanced filters: Author: Michelle L. Reniere Clear advanced filters

Glutathione activates virulence gene expression of an intracellular pathogen

This study shows that glutathione, a ubiquitous antioxidant, is also a critical signalling molecule that allosterically activates the master virulence regulator in the intracellular pathogen Listeria monocytogenes.

Michelle L. Reniere
Aaron T. Whiteley
Daniel A. Portnoy
Research07 Jan 2015
Nature

Volume: 517, P: 170-173
Genome-wide protein–DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase

A method that exploits the double-stranded DNA-targeting capability of the bacterial toxin-derived cytosine deaminase, DddA, can map DNA–protein interactions in bacteria in vivo at genome-wide scale.

Larry A. Gallagher
Elena Velazquez
Joseph D. Mougous
ResearchOpen Access01 Jun 2022
Nature Microbiology

Volume: 7, P: 844-855

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Glutathione activates virulence gene expression of an intracellular pathogen

Genome-wide protein–DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase

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