Nature Search

Origin of the Potential Difference in the Intestinal Epithelium of the Turtle

MICHELLE BAILLIEN
E. SCHOFFENIELS
Research17 Jun 1961
Nature

Volume: 190, P: 1107-1108
Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer’s disease

Caloric restriction improves Alzheimer’s Disease outcomes in mice, but this diet not only reduces calories, but imposes a prolonged fast between meals. Here, the authors show this fast is essential to improve Alzheimer’s pathology and cognition.

Reji Babygirija
Jessica H. Han
Dudley W. Lamming
ResearchOpen Access04 Aug 2025
Nature Communications

Volume: 16, P: 1-20
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Casein kinase 2 reverses tail-independent inactivation of kinesin-1

Kinesin-1 is a motor protein that transports cargo along microtubules and defects in this process can result in neurodegeneration. In this study, a role for casein kinase 2 in regulating the activity of Kinesin-1 is reported, suggesting that signalling molecules can modulate this transport process.

Jing Xu
Babu J. N. Reddy
Steven P. Gross
Research27 Mar 2012
Nature Communications

Volume: 3, P: 1-12
Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma

Swanton and colleagues present a clonal expression signature, ORACLE, which, in combination with clinicopathological and molecular risk factors, can predict survival of patients with lung adenocarcinoma, and they prospectively validate its prognostic value.

Dhruva Biswas
Yun-Hsin Liu
Charles Swanton
ResearchOpen Access09 Jan 2025
Nature Cancer

Volume: 6, P: 86-101
Load-induced enhancement of Dynein force production by LIS1–NudE in vivo and in vitro

Transport of large cargo through the cytoplasm can encounter physical impediments which should be overcome. Here the authors show that lipid droplets constrained by an optical trap respond with an increase in dynein-mediated force that is dependent on dynein regulators LIS1 and NudE/L, but not on p150^glued.

Babu J. N. Reddy
Michelle Mattson
Steven P. Gross
ResearchOpen Access04 Aug 2016
Nature Communications

Volume: 7, P: 1-14
Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

Shi-Dong Chen
Jia-Ying Lu
Michelle Zmuda
ResearchOpen Access18 Sept 2021
Translational Psychiatry

Volume: 11, P: 1-12
Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

The tau protein is theorized to spread transneuronally in Alzheimers disease, though this theory remains unproven in humans. Our simulations of epidemic-like protein spreading across human brain networks support this theory, and suggest the spreading dynamics are modified by β-amyloid

Jacob W. Vogel
Yasser Iturria-Medina
Per Wollmer
ResearchOpen Access26 May 2020
Nature Communications

Volume: 11, P: 1-15
Randomised controlled trial of intermittent vs continuous energy restriction during chemotherapy for early breast cancer

Michelle Harvie
Mary Pegington
Anthony Howell
ResearchOpen Access15 Dec 2021
British Journal of Cancer

Volume: 126, P: 1157-1167
Cooperative protofilament switching emerges from inter-motor interference in multiple-motor transport

David Ando
Michelle K. Mattson
Ajay Gopinathan
ResearchOpen Access01 Dec 2014
Scientific Reports

Volume: 4, P: 1-8
Author Correction: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

Jacob W. Vogel
Yasser Iturria-Medina
Per Wollmer
Amendments and CorrectionsOpen Access05 Aug 2021
Nature Communications

Volume: 12, P: 1
The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

M N Harvie
M Pegington
A Howell
Research05 Oct 2010
International Journal of Obesity

Volume: 35, P: 714-727

Search

Origin of the Potential Difference in the Intestinal Epithelium of the Turtle

Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer’s disease

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Casein kinase 2 reverses tail-independent inactivation of kinesin-1

Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma

Load-induced enhancement of Dynein force production by LIS1–NudE in vivo and in vitro

Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

Randomised controlled trial of intermittent vs continuous energy restriction during chemotherapy for early breast cancer

Cooperative protofilament switching emerges from inter-motor interference in multiple-motor transport

Author Correction: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

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