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Showing 1–5 of 5 results

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Author Correction: Autotaxin–lysolipid signaling suppresses a CCL11–eosinophil axis to promote pancreatic cancer progression

Sohinee Bhattacharyya
Chet Oon
Mara H. Sherman
Amendments and CorrectionsOpen Access23 Jul 2025
Nature Cancer

Volume: 6, P: 1477
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria

Mitochondria are able to maintain two competing metabolic pathways—oxidative phosphorylation and the reductive synthesis of proline and ornithine—by generating two mitochondrial subpopulations that are enriched in either pyrroline-5-carboxylate synthase or ATP synthase.

Keun Woo Ryu
Tak Shun Fung
Craig B. Thompson
Research06 Nov 2024
Nature

Volume: 635, P: 746-754
Autotaxin–lysolipid signaling suppresses a CCL11–eosinophil axis to promote pancreatic cancer progression

Sherman and colleagues show that ATX suppresses the accumulation of eosinophils in the tumor microenvironment of pancreatic cancer via suppression of CCL11 expression and find that ATX inhibition increases eosinophil influx, promoting tumor cell death.

Sohinee Bhattacharyya
Chet Oon
Mara H. Sherman
ResearchOpen Access09 Jan 2024
Nature Cancer

Volume: 5, P: 283-298
M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome

CQ31 inhibits the M24B aminopeptidases prolidase and Xaa-Pro aminopeptidase 1 leading to increased proline-containing peptides that block dipeptidyl peptidases 8 and 9 activity resulting in the activation of the CARD8 inflammasome.

Sahana D. Rao
Qifeng Chen
Daniel A. Bachovchin
Research14 Feb 2022
Nature Chemical Biology

Volume: 18, P: 565-574
Placental Metabolomics for Assessment of Sex-specific Differences in Fetal Development During Normal Gestation

Michelle Saoi
Katherine M. Kennedy
Philip Britz-McKibbin
ResearchOpen Access10 Jun 2020
Scientific Reports

Volume: 10, P: 1-10