Nature Search

Responses of pink salmon to CO₂-induced aquatic acidification

Pink salmon start life in fresh water before moving to the sea. This study shows that CO₂-induced acidification due to climate change detrimentally affects salmon physiology and behaviour in fresh water and shortly following seawater entry.

Michelle Ou
Trevor J. Hamilton
Colin J. Brauner
Research29 Jun 2015
Nature Climate Change

Volume: 5, P: 950-955
c-Jun overexpression in CAR T cells induces exhaustion resistance

Chimeric antigen receptor (CAR) T cells engineered to overexpress the canonical AP-1 transcription factor c-Jun are resistant to T cell exhaustion, and provide enhanced therapeutic benefit in mouse tumour models.

Rachel C. Lynn
Evan W. Weber
Crystal L. Mackall
Research04 Dec 2019
Nature

Volume: 576, P: 293-300
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

A randomized trial in patients hospitalized with COVID-19 showed no benefit and potentially increased harm associated with the use of convalescent plasma, with subgroup analyses suggesting that the antibody profile in donor plasma is critical in determining clinical outcomes.

Philippe Bégin
Jeannie Callum
Donald M. Arnold
ResearchOpen Access09 Sept 2021
Nature Medicine

Volume: 27, P: 2012-2024
Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3

Clemons and colleagues identify a guided entry of tail-anchored proteins (GET) pathway in the pathogen Giardia intestinalis and characterize it structurally, revealing several previously unknown structures of the central protein Get3. The work resolves some important open questions and results in a comprehensive model for the insertion of tail-anchored membrane proteins.

Michelle Y. Fry
Vladimíra Najdrová
William M. Clemons Jr
Research18 Jul 2022
Nature Structural & Molecular Biology

Volume: 29, P: 820-830
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome

Eamonn Sheridan, Elizabeth Ross and colleagues report discovery of a new megalencephaly syndrome caused by de novo missense mutations in CCND2. They show that these mutations lead to stabilization of cyclin D2, and they present evidence that cyclin D2 stabilization may be a common downstream mechanism in PI3K-AKT–associated megalencephaly syndromes.

Ghayda M Mirzaa
David A Parry
Eamonn G Sheridan
Research06 Apr 2014
Nature Genetics

Volume: 46, P: 510-515
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Amendments and CorrectionsOpen Access12 Jan 2022
Nature Medicine

Volume: 28, P: 212
Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C

Michelle J. Hayes
Yuu Kimata
Andrew M. Fry
Research30 Apr 2006
Nature Cell Biology

Volume: 8, P: 607-614
Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration

CRISPR-Cas13 mediated editing of RNA corrects a common mutation in the retinal degeneration gene USH2A, and restores usherin expression in mouse photoreceptors when delivered with adeno-associated viral gene therapy.

Lewis E. Fry
Lauren Major
Robert E. MacLaren
ResearchOpen Access08 Feb 2025
Communications Biology

Volume: 8, P: 1-16
A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection

Simon P. Preston
Cody C. Allison
Marc Pellegrini
ResearchOpen Access15 Feb 2023
Cell Death & Disease

Volume: 14, P: 1-10
α5 and α2 Integrin Gene Transfers Mimic the PDGF-B–Induced Transformed Phenotype of Fibroblasts in Human Skin

Mark Nesbit
Helmut Schaider
Meenhard Herlyn
Research01 Sept 2001
Laboratory Investigation

Volume: 81, P: 1263-1274
Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States

Detailed clinical and virologic characteristics of the first 12 individuals with COVID-19 in the United States from the US Centers for Disease Control and Prevention.

Stephanie A. Kujawski
Karen K. Wong
Jing Zhang
Research23 Apr 2020
Nature Medicine

Volume: 26, P: 861-868
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22
Lung cancer in never smokers (LCINS): development of a UK national research strategy

Sam Khan
Nathaniel Hatton
Matthew Hatton
ReviewsOpen Access20 Jul 2023
BJC Reports

Volume: 1, P: 1-9

Search

Responses of pink salmon to CO₂-induced aquatic acidification

c-Jun overexpression in CAR T cells induces exhaustion resistance

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3

De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome

Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C

Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration

A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection

α5 and α2 Integrin Gene Transfers Mimic the PDGF-B–Induced Transformed Phenotype of Fibroblasts in Human Skin

Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Lung cancer in never smokers (LCINS): development of a UK national research strategy

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