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Showing 1–10 of 10 results
Advanced filters: Author: Mick F. Tuite Clear advanced filters
    • Mick F. Tuite
    • Ian Stansfield
    News & Views
    Nature
    Volume: 372, P: 614-615
  • Epigenetic mechanisms participate in the regulation of gene transcription in eukaryotes. Two studies in yeast have revealed an additional mechanism for controlling global gene transcription that is based on an inherited self-perpetuating change in the conformation of two different components of key transcriptional regulatory complexes.

    • Mick F. Tuite
    • Brian S. Cox
    News & Views
    Nature Cell Biology
    Volume: 11, P: 241-243
  • Mammalian prions are typically associated with the development of neurodegenerative diseases. However, prions in fungi act as epigenetic determinants. The similarities between mammalian and fungal prions suggest that, rather than being a biological anomaly, prions might instead function as regulators of cell phenotype.

    • Mick F. Tuite
    • Tricia R. Serio
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 11, P: 823-833
  • Prions are remarkable infectious agents associated with certain brain diseases. But they also occur in fungi, experiments with which now provide plausible answers to some critical questions about prion biology.

    • Mick F. Tuite
    News & Views
    Nature
    Volume: 428, P: 265-267
  • Prion-forming proteins have been found in animals, plants, fungi, and bacteria. Here, Nan et al. report that a baculovirus-encoded protein behaves as prion in a yeast system and forms aggregates at high multiplicity of infection in insect cells that affect baculovirus replication.

    • Hao Nan
    • Hongying Chen
    • Xiaodong Xu
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11
  • A single amyloid-forming protein or peptide can adopt many different fibrillar 3D structures, but this polymorphism is poorly understood. Here, detailed AFM imaging allows for the reconstruction of 3D models of individual fibrils which can be clustered on the basis of their individual structural properties.

    • Liam D. Aubrey
    • Ben J. F. Blakeman
    • Wei-Feng Xue
    ResearchOpen Access
    Communications Chemistry
    Volume: 3, P: 1-10