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Showing 1–2 of 2 results
Advanced filters: Author: Mikael V. Garabedian Clear advanced filters
  • Cells spatially organize biochemical reactions within membrane-bound and membraneless compartments. The extent to which intrinsically disordered proteins themselves can form discrete compartments or condensed phases is poorly understood. Now a pair of model IDRs that display orthogonality in condensation and the chain features governing selective assembly have been identified.

    • Rachel M. Welles
    • Kandarp A. Sojitra
    • Matthew C. Good
    Research
    Nature Chemistry
    Volume: 16, P: 1062-1072
  • Controlled assembly of synthetic intracellular condensates from engineered disordered proteins enables control of cellular activities such as proliferation and division through recruitment, sequestration and insulation of endogenous client proteins.

    • Mikael V. Garabedian
    • Wentao Wang
    • Matthew C. Good
    Research
    Nature Chemical Biology
    Volume: 17, P: 998-1007