Nature Search

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Genome-wide association studies (GWAS) have improved our understanding of the genetic basis of lung adenocarcinoma but known susceptibility variants explain only a small fraction of the familial risk. Here, the authors perform a two-stage GWAS and report 12 novel genetic loci associated with lung adenocarcinoma in East Asians.

Jianxin Shi
Kouya Shiraishi
Qing Lan
ResearchOpen Access26 May 2023
Nature Communications

Volume: 14, P: 1-17
Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug

Integrated structural biology approach leveraging in situ cryo-electron tomography reveals molecular details of the native malarial translation elongation cycle and its perturbation by cabamiquine, a potent antimalarial drug candidate.

Leonie Anton
Wenjing Cheng
Chi-Min Ho
ResearchOpen Access18 Aug 2025
Nature Structural & Molecular Biology

Volume: 32, P: 2158-2164
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Qing Lan and colleagues report the results of a genome-wide association study of lung cancer in never-smoking women from Asia. They identify three new susceptibility loci and confirm three other previously reported associations.

Qing Lan
Chao A Hsiung
Nathaniel Rothman
Research11 Nov 2012
Nature Genetics

Volume: 44, P: 1330-1335
Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1

Qiuyin Cai and colleagues report a genome-wide association analysis for breast cancer in 22,780 cases and 24,181 controls from 14 studies as part of the Asia Breast Cancer Consortium. They identify three loci newly associated with breast cancer susceptibility.

Qiuyin Cai
Ben Zhang
Wei Zheng
Research20 Jul 2014
Nature Genetics

Volume: 46, P: 886-890
Synergetic electrode architecture for efficient graphene-based flexible organic light-emitting diodes

Replacing indium tin oxide with graphene in organic light-emitting diodes is a promising approach to enhance the flexibility of displays and light sources. Here, the authors combine graphene, TiO₂and low-index hole-injection layers to achieve high external quantum efficiency and good bendability.

Jaeho Lee
Tae-Hee Han
Seunghyup Yoo
ResearchOpen Access02 Jun 2016
Nature Communications

Volume: 7, P: 1-9
Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets

Jae-We Cho
Kun Park
Seong-Il Suh
ResearchOpen Access01 Jun 2005
Experimental & Molecular Medicine

Volume: 37, P: 186-192
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

Wei Zheng and colleagues report the results of a large-scale genome-wide association study of colorectal cancer in East Asians. They identify six new susceptibility loci, including variants near TCF7L2 and TGFB1.

Ben Zhang
Wei-Hua Jia
Wei Zheng
Research18 May 2014
Nature Genetics

Volume: 46, P: 533-542
Fully bioresorbable hybrid opto-electronic neural implant system for simultaneous electrophysiological recording and optogenetic stimulation

Bioresorbable neural implants offer a promising solution to the challenges of secondary surgeries required for the removal of implanted devices. Here, the authors introduce a fully bioresorbable flexible hybrid opto-electronic system for simultaneous electrophysiological recording and optogenetic stimulation.

Myeongki Cho
Jeong-Kyu Han
Ki Jun Yu
ResearchOpen Access06 Mar 2024
Nature Communications

Volume: 15, P: 1-16
Photocurable bioresorbable adhesives as functional interfaces between flexible bioelectronic devices and soft biological tissues

A functional interfacial material has been developed for soft integration of bioelectronic devices with biological tissues. This has been applied in battery-free optoelectronic systems for deep-brain optogenetics and subdermal phototherapy as well as wireless millimetre-scale pacemakers and flexible multielectrode epicardial arrays.

Quansan Yang
Tong Wei
John A. Rogers
Research29 Jul 2021
Nature Materials

Volume: 20, P: 1559-1570
Impact of Overweight/Obesity on Clinical Outcomes of Patient with Vasospastic Angina: From the Vasospastic Angina in Korea Registry

Min-Ho Lee
Sang-Ho Jo
Won-Woo Seo
ResearchOpen Access18 Mar 2020
Scientific Reports

Volume: 10, P: 1-9
The trisaccharide raffinose modulates epidermal differentiation through activation of liver X receptor

Tae-Young Na
Gyeong-Hwan Kim
Mi-Ock Lee
ResearchOpen Access07 Mar 2017
Scientific Reports

Volume: 7, P: 1-10
High production of CH₄ and H₂ by reducing PET waste water using a non-diaphragm-based electrochemical method

Nam-Gyu Kim
Kwang-Jin Yim
Tae-Oh Kim
ResearchOpen Access04 Feb 2016
Scientific Reports

Volume: 6, P: 1-9
Probing graphene grain boundaries with optical microscopy

A simple method to observe grain boundaries in graphene is reported, using ultraviolet irradiation in humid conditions followed by optical microscopy.

Dinh Loc Duong
Gang Hee Han
Young Hee Lee
Research03 Oct 2012
Nature

Volume: 490, P: 235-239
Assessing the impact of mRNA vaccination in chronic inflammatory murine model

Seonghyun Lee
Jisun Lee
Jae-Hwan Nam
ResearchOpen Access15 Feb 2024
npj Vaccines

Volume: 9, P: 1-12
Admission serum potassium levels and prognosis of vasospastic angina

Won-Woo Seo
Sang-Ho Jo
Sang Hong Baek
ResearchOpen Access11 Mar 2021
Scientific Reports

Volume: 11, P: 1-9
Clopidogrel plus Aspirin Use is Associated with Worse Long-Term Outcomes, but Aspirin Use Alone is Safe in Patients with Vasospastic Angina: Results from the VA-Korea Registry, A Prospective Multi-Center Cohort

Seong-Sik Cho
Sang-Ho Jo
Sang Hong Baek
ResearchOpen Access28 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
Approaching ultimate flexible organic light-emitting diodes using a graphene anode

We realized highly flexible tandem OLEDs using a graphene anode with very high electroluminescent efficiency ~205.9 cd A⁻¹, 45.2% (~396.4 cd A⁻¹, 87.3% with a hemispherical lens) and very low efficiency roll-off at high luminance ~6.6% at 10 000 cd m⁻² (~3.8% with a hemispherical lens) by stacking two organic electroluminescence units using a easily controllable and low-temperature processable charge generation layer on thin flexible plastic substrates. The flexible OLEDs showed great flexibility against bending stress up to bending strain of 6.7%.

Tae-Hee Han
Min-Ho Park
Tae-Woo Lee
ResearchOpen Access09 Sept 2016
NPG Asia Materials

Volume: 8, P: e303
Stroke in Traditional Korean Medicine: A Nine-Year Multicentre Community-Based Study in South Korea

Mi Mi Ko
Ju Ah Lee
Myeong Soo Lee
ResearchOpen Access22 Jun 2016
Scientific Reports

Volume: 6, P: 1-9
Towards a comprehensive understanding of FeCo coated with N-doped carbon as a stable bi-functional catalyst in acidic media

FeCo@N—C nanoparticle as a bi-functional catalyst in both oxygen reduction reaction and hydrogen evolution reaction.

Seung Hyo Noh
Min Ho Seo
Takeo Ohsaka
ResearchOpen Access23 Sept 2016
NPG Asia Materials

Volume: 8, P: e312
Universal high work function flexible anode for simplified ITO-free organic and perovskite light-emitting diodes with ultra-high efficiency

We report a new anode material that has multifunction of both an anode and a hole injection layer (HIL) as a single layer. Our anode has easy work function tunability up to 5.8 eV and thus makes ohmic contact without any HIL. We applied our anodes to simplified organic light-emitting diodes, resulting in high efficiency (62% ph el⁻¹ for single and 88% ph el⁻¹ for tandem). Our anode showed a similar tendency in simplified perovskite light-emitting diodes. We also demonstrated large-area flexible lightings using our anodes. Our results provide a significant step toward the next generation of high-performance simplified light-emitting diodes.

Su-Hun Jeong
Seong-Hoon Woo
Tae-Woo Lee
ResearchOpen Access28 Jul 2017
NPG Asia Materials

Volume: 9, P: e411

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