Shao et al. show that a bacterial symbiont drives its fungal host to biosynthesize a polyketide antimicrobial, spiromarmycin, fending off their competitors. They find that the spiromarmycin biosynthetic machinery is encoded by the fungal host. This study provides insights into the evolution of marine microbial diversity.
- Mingwei Shao
- Changli Sun
- Jianhua Ju
