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Showing 1–4 of 4 results
Advanced filters: Author: Mingyun Bae Clear advanced filters

  • Histone variants act as transcriptional activators and repressors and have been linked to cancer progression. Park and Choi et al. show that the histone H3.3 overexpression is associated with early-stage lung cancer, and promotes cancer cell migration by upregulating a G-protein-coupled receptor.

    • Seong-Min Park
    • Eun-Young Choi
    • In-Hoo Kim
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-14

  • The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

    • Tim H. H. Coorens
    • Ji Won Oh
    • Yuqing Wang
    Reviews
    Nature
    Volume: 643, P: 47-59

  • Jung Kyoon Choi and colleagues identify sets of regulatory mutations in breast and lung cancer samples that converge on the same gene target across individual samples. They use features of these mutation sets to develop a method for predicting functionally recurrent regulatory mutations that may function as drivers in cancer.

    • Kwoneel Kim
    • Kiwon Jang
    • Jung Kyoon Choi
    Research
    Nature Genetics
    Volume: 48, P: 1321-1326