The transcriptional repressor Zbtb46 is expressed by DCs and endothelial cells. In this study, Choi and colleagues find downregulation of Zbtb46 confers a pro-tumor program in the vasculature and hematopoietic system, by promoting angiogenesis and the development of immunosuppressive myeloid cells.
- Ashraf Ul Kabir
- Carisa Zeng
- Kyunghee Choi
