Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–8 of 8 results
Advanced filters: Author: Misha Bilenky Clear advanced filters

  • This study describes the integrative analysis of 111 reference human epigenomes, profiled for histone modification patterns, DNA accessibility, DNA methylation and RNA expression; the results annotate candidate regulatory elements in diverse tissues and cell types, their candidate regulators, and the set of human traits for which they show genetic variant enrichment, providing a resource for interpreting the molecular basis of human disease.

    • Anshul Kundaje
    • Wouter Meuleman
    • Manolis Kellis
    ResearchOpen Access
    Nature
    Volume: 518, P: 317-330

  • Epigenetic changes associated with post-natal differentiation have been characterized. Here the authors generate epigenomic and transcriptional profiles from primary human breast cells, providing insights into the transcriptional and epigenetic events that define post-natal cell differentiation in vivo.

    • Philippe Gascard
    • Misha Bilenky
    • Martin Hirst
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-10

  • Hematopoietic stem cell formation via the endothelial-to-hematopoietic transition is initiated by a complex rewiring of the aortic endothelium. Here the authors identify Meis1 as an early driver of hemogenic specification of this arterial endothelium.

    • Patrick Coulombe
    • Grace Cole
    • Aly Karsan
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • Epigenomes are thought to retain molecular memories of their developmental history. Here, by comparing differentially methylated regions of genomes from different cells, the authors reveal an epigenetic signature that underlies a shared gene regulatory network with a common developmental origin.

    • Rebecca F. Lowdon
    • Bo Zhang
    • Jeffrey B. Cheng
    Research
    Nature Communications
    Volume: 5, P: 1-11

  • Many loci in the mammalian genome are intermediately methylated. Here, by comprehensively identifying these loci and quantifying their relationship with gene activity, the authors show that intermediate methylation is an evolutionarily conserved epigenomic signature of gene regulation.

    • GiNell Elliott
    • Chibo Hong
    • Joseph F. Costello
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-10

  • The first formal evidence of the shared and independent ability of basal cells and luminal pro-genitors isolated from normal human mammary tissue and transduced with a single oncogene to initiate tumorigeneses when introduced into mice.

    • Long V. Nguyen
    • Davide Pellacani
    • Connie J. Eaves
    Research
    Nature
    Volume: 528, P: 267-271