Nature Search

Progress in the development of cytokine armoured CAR T cells

Cytokine-armoured CAR T cells represent a new generation of programmable cell therapies designed to enhance efficacy while limiting toxicity. This Review explores how cytokine armouring and advances in synthetic receptor design and conditional gene circuits are reshaping immunotherapy for solid tumours.

Krishneel Prasad
Ryan S. Cross
Misty R. Jenkins
Reviews06 Mar 2026
Nature Reviews Immunology

P: 1-13
TIRE-seq simplifies transcriptomics via integrated RNA capture and library preparation

Piper O’Keeffe
Yasmin Nouri
Daniel V. Brown
ResearchOpen Access02 May 2025
Scientific Reports

Volume: 15, P: 1-12
Indigenous Australian genomes show deep structure and rich novel variation

Analysis of the genomes of 159 individuals from four Indigenous communities in Australia shows a high level of genetic variation and demonstrates the need for greater representation of Indigenous Australians in reference panels and clinical databases.

Matthew Silcocks
Ashley Farlow
Stephen Leslie
ResearchOpen Access13 Dec 2023
Nature

Volume: 624, P: 593-601
The landscape of genomic structural variation in Indigenous Australians

Population-scale whole-genome sequencing across four remote Indigenous Australian communities reveals a large fraction of structural variants that are unique to these populations, emphasizing the genetic distinctiveness of and diversity among Indigenous Australians.

Andre L. M. Reis
Melissa Rapadas
Ira W. Deveson
ResearchOpen Access13 Dec 2023
Nature

Volume: 624, P: 602-610
Defining the extracellular matrix for targeted immunotherapy in adult and pediatric brain cancer

Zoe I. Day
Samuel Roberts-Thomson
Misty R. Jenkins
ResearchOpen Access14 Jun 2025
npj Precision Oncology

Volume: 9, P: 1-14
Investigating disparity in access to Australian clinical genetic health services for Aboriginal and Torres Strait Islander people

Globally it is recognised that Indigenous populations should be able to access the benefits of genomics and precision medicine. Here, authors show that there are disparities in access to clinical genetic health services for Aboriginal and/or Torres Strait Islander people in Australia.

Joanne Luke
Philippa Dalach
Margaret Kelaher
ResearchOpen Access24 Aug 2022
Nature Communications

Volume: 13, P: 1-11
Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma

Nicholas A. Gherardin
Liyen Loh
Dale I. Godfrey
ResearchOpen Access07 Mar 2018
Scientific Reports

Volume: 8, P: 1-14
BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Diane Moujalled
Adam G. Southon
Andreas Strasser
Research24 Mar 2022
Cell Death & Differentiation

Volume: 29, P: 1335-1348
From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress

Brittany Dewdney
Misty R. Jenkins
Terrance G. Johns
ReviewsOpen Access20 Oct 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-33

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