Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Moiez Ali Clear advanced filters

  • KRAS mutations drive resistance to diverse targeted therapies. In this study, the authors show that the rare codons of KRAS, yielding low oncogene expression, can be overcome to drive resistance to anti-EGFR therapy in CRC through upregulation of global translation or through selection of more potent KRASQ61mutations.

    • Moiez Ali
    • Erin Kaltenbrun
    • Kris C. Wood
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11

  • Mitochondrial dynamics regulate critical processes. Here the authors show that genes regulating mitochondrial dynamics are frequently amplified in human cancers, and that these alterations are associated with changes in drug sensitivity including increased sensitivity to the apoptosis-targeting Smac mimetics.

    • Gray R. Anderson
    • Suzanne E. Wardell
    • Kris C. Wood
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13