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Showing 1–3 of 3 results
Advanced filters: Author: Moises Freitas-Andrade Clear advanced filters

  • Despite a wealth of knowledge on astrocytes, their contribution to cerebrovascular maturation is less known. Here, the authors identify a molecule produced by astrocytes which controls astrocyte morphology and their placement on brain blood vessels.

    • Moises Freitas-Andrade
    • Cesar H. Comin
    • Baptiste Lacoste
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-20

  • Most studies of autism spectrum disorder (ASD) have focused on neuronal mechanisms. Here, the authors describe vascular impairments in a mouse model of 16p11.2 deletion syndrome using physiological and genetic approaches to examine endothelial-dependent phenotypes.

    • Julie Ouellette
    • Xavier Toussay
    • Baptiste Lacoste
    Research
    Nature Neuroscience
    Volume: 23, P: 1090-1101

  • In order to advance our understanding of the effects of maternal high-fat diet (mHFD) on the cerebrovascular health of offspring, Bordeleau et al. use a translational mouse model of mHFD exposure. They demonstrate that mHFD induces cerebrovascular and microglial changes in the offspring as well as behavioural alterations that are reminiscent of neurodevelopmental disorders associated with repetitive behaviours at adulthood.

    • Maude Bordeleau
    • Cesar H. Comin
    • Marie-Ève Tremblay
    ResearchOpen Access
    Communications Biology
    Volume: 5, P: 1-13