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Showing 1–5 of 5 results
Advanced filters: Author: Molly F. Parsons Clear advanced filters
  • Hybrid nucleic acid origami has potential for biomedical delivery of mRNA and fabrication of artificial ribozymes. Here, the authors use chemical footprinting and cryo-electron microscopy to reveal insights into nucleic acid origami used to fold messenger and ribosomal RNA into 3D polyhedral structures.

    • Molly F. Parsons
    • Matthew F. Allan
    • Mark Bathe
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14
  • Programming the 3D spatial organization of quantum dots requires precise control over their individual valence, but this is challenging due to the possible presence of multiple binding sites. Here, authors develop a general approach that uses highly programmable wireframe DNA origami structures to control the 3D spatial relationships between QDs and other non-nucleic-acid molecules.

    • Chi Chen
    • Xingfei Wei
    • Mark Bathe
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15
  • Identifying the mutational landscape of tumours from cell-free DNA in the blood could help diagnostics in cancer. Here, the authors present ichorCNA, software that quantifies tumour content in cell free DNA, and they demonstrate that cell-free DNA whole-exome sequencing is concordant with metastatic tumour whole-exome sequencing.

    • Viktor A. Adalsteinsson
    • Gavin Ha
    • Matthew Meyerson
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-13