The glomerular endothelial glycocalyx lines the glomerular capillaries and contributes to the ability of these specialized blood vessels to limit protein permeability. This Review describes how dysfunction of the glomerular endothelial glycocalyx contributes to the development of proteinuria in glomerular disease and potential therapeutic approaches to protect or restore it.
- Monica Gamez
- Raina D. Ramnath
- Simon C. Satchell
