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Showing 1–4 of 4 results
Advanced filters: Author: Moran Choe Clear advanced filters

  • Tumour necroptosis is regulated by RIPK3 during tumour development. Here the authors show that ZBP1 is an upstream mediator of RIPK3 in tumour necroptosis and that glucose deprivation induces the release of mitochondrial DNA, which binds to ZBP1 to activate ZBP1-mediated necroptosis in breast cancer.

    • Jin Young Baik
    • Zhaoshan Liu
    • Zheng-gang Liu
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • A system employing liquid-handling robotics and an integrated mobile microscope enables the automated culture, sample collection and in situ microscopy imaging of up to ten fluidically coupled organ chips within a standard tissue-culture incubator.

    • Richard Novak
    • Miles Ingram
    • Donald E. Ingber
    Research
    Nature Biomedical Engineering
    Volume: 4, P: 407-420

  • The molecular switch between how tumour necrosis factor (TNF) controls inflammation versus cell death is less well defined. Here, the authors show that the nuclear receptor retinoic acid receptor gamma is released from the nucleus to disrupt TNF initiated cell death complexes in the cytoplasm.

    • Qing Xu
    • Siriporn Jitkaew
    • Zheng-gang Liu
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-15