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Nature Communications (2)

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Advanced filters: Author: Mordechai Choder Clear advanced filters

RNA-controlled nucleocytoplasmic shuttling of mRNA decay factors regulates mRNA synthesis and a novel mRNA decay pathway

Nucleocytoplasmic shuttling of several yeast mRNA decay factors regulates transcription and initiates a novel mRNA decay pathway; shuttling is controlled by the decaying RNA and is critical for coping with environmental changes.

Shiladitya Chattopadhyay
Jose Garcia-Martinez
Mordechai Choder
ResearchOpen Access23 Nov 2022
Nature Communications

Volume: 13, P: 1-17
The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins

The exonuclease Xrn1 mediates crosstalk between transcription and mRNA decay in yeast. Here the authors demonstrate that Xrn1 promotes translation of mRNAs encoding membrane proteins, coupling transcription, translation, and mRNA decay.

Bernat Blasco-Moreno
Leire de Campos-Mata
Juana Díez
ResearchOpen Access21 Mar 2019
Nature Communications

Volume: 10, P: 1-15

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RNA-controlled nucleocytoplasmic shuttling of mRNA decay factors regulates mRNA synthesis and a novel mRNA decay pathway

The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins

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