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PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer

PTEN is often lost in prostate cancer. In this study, the authors show that PTEN can act as a protein phosphatase that targets active PTK6, thereby regulating its oncogenic signaling in prostate cancer progression.

Darren J. Wozniak
Andre Kajdacsy-Balla
Angela L. Tyner
ResearchOpen Access15 Nov 2017
Nature Communications

Volume: 8, P: 1-13

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PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer

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