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Showing 1–2 of 2 results
Advanced filters: Author: Morgan Thenoz Clear advanced filters

  • The nuclear factors κB (NF-κB) is a transcription factor involved in immune functions, inflammation, and cancer. Here, the authors show that the NF-κB factor RELA regulates splicing of target genes by recruiting DDX17 on chromatin upon expression of the viral oncogene Tax.

    • Lamya Ben Ameur
    • Paul Marie
    • Franck Mortreux
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • T-acute lymphoblastic leukemia is an aggressive cancer. Here the authors provide insights into the functional role of SHQ1, an H/ACA snoRNP assembly factor involved in snRNA pseudouridylation, in T-lymphoblastic leukemia cell survival through regulating the maturation of MYC mRNA.

    • Hexiu Su
    • Juncheng Hu
    • Hudan Liu
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15