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Showing 1–2 of 2 results
Advanced filters: Author: Moritz Jakab Clear advanced filters

  • Jakab et al. show that metastasizing tumor cells have a predetermined methylation status that allows them to respond differentially to endothelial cell niche-derived Wnt signals, resulting in either latency or intravascular proliferation.

    • Moritz Jakab
    • Ki Hong Lee
    • Hellmut G. Augustin
    ResearchOpen Access
    Nature Cancer
    Volume: 5, P: 716-730

  • A highly potent and selective small-molecule catalytic inhibitor of the protein lysine methyltransferase NSD2 shows therapeutic efficacy in preclinical models of KRAS-driven pancreatic cancer and lung cancer.

    • Jinho Jeong
    • Simone Hausmann
    • Or Gozani
    Research
    Nature
    Volume: 649, P: 205-215