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Showing 1–2 of 2 results
Advanced filters: Author: Mostafa Ghannad-Rezaie Clear advanced filters

  • Brain disorders are associated with network dysfunctions that are not addressed by conventional drug screens. Here, the authors use high-throughput functional imaging of brain activity in zebrafish larvae to study the effects of individual drugs on network connectivity and demonstrate an algorithm that predicts the most effective drug combinations to normalize both the activity patterns and the animal behavior.

    • Mostafa Ghannad-Rezaie
    • Peter M. Eimon
    • Mehmet Fatih Yanik
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13

  • One challenge in drug screening for neurological disorders is how to accurately capture disease pathology and side effects. Here, the authors developed a multi-channel recording platform based on a zebrafish genetic model of epilepsy to screen for antiepileptic drugs.

    • Peter M. Eimon
    • Mostafa Ghannad-Rezaie
    • Mehmet Fatih Yanik
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14