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Showing 1–2 of 2 results
Advanced filters: Author: Moushumi Das Clear advanced filters

  • In the nematode C. elegans, cohesin creates specifically at active enhancers chromatin 3D structures named fountains. Cohesin artificial cleavage disrupts fountains and changes neuronal gene expression, function and animal behavior.

    • Bolaji N. Lüthi
    • Jennifer I. Semple
    • Peter Meister
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-20

  • Inactivation of somatic SMC complexes in Caenorhabditis elegans shows that condensin I is the major long-range genome loop extruder, while cohesin forms small loops. Inactivation of cohesin, condensin II and condensin I/IDC causes minor transcriptional changes in autosomes.

    • Moushumi Das
    • Jennifer I. Semple
    • Peter Meister
    Research
    Nature Genetics
    Volume: 56, P: 1737-1749