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Advanced filters: Author: Mudra Patel Clear advanced filters

  • The heart relies on fatty acid oxidation as its main energy source. Here they show that impaired fatty acid metabolism disrupts mitophagy in the heart and that enhancing mitophagy via USP30 inhibition can restore heart function in models of fatty acid oxidation deficiency.

    • Nuo Sun
    • Hayley Barta
    • Toren Finkel
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15