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Showing 1–5 of 5 results
Advanced filters: Author: Nadine Kaesler Clear advanced filters

  • A range of techniques are used to investigate the molecular landscape of chronic kidney disease, and the results suggest that distinct populations of pericytes and fibroblasts are the main source of myofibroblasts in kidney fibrosis.

    • Christoph Kuppe
    • Mahmoud M. Ibrahim
    • Rafael Kramann
    Research
    Nature
    Volume: 589, P: 281-286

  • A time-resolved high-resolution map of human cardiac remodelling after myocardial infarction, integrating single-cell transcriptomic, chromatin accessibility and spatial transcriptomic data, provides a valuable resource for the field.

    • Christoph Kuppe
    • Ricardo O. Ramirez Flores
    • Rafael Kramann
    Research
    Nature
    Volume: 608, P: 766-777

  • The cardiac vascular niche is of major importance in homeostasis and disease, but knowledge of its complexity in response to injury remains limited. Here we combine lineage tracing with single cell RNA sequencing to show alterations in fibroblasts, endothelial and mural cells in hypertrophic remodeling.

    • Fabian Peisker
    • Maurice Halder
    • Rafael Kramann
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-20