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Showing 1–4 of 4 results
Advanced filters: Author: Nanditha Rajamani Clear advanced filters

  • Different motor symptoms respond variably to deep brain stimulation in Parkinson’s Disease. Rajamani et al. suggest that this variability may be due to tremor, bradykinesia, rigidity, and axial symptoms being associated with a gradient of brain circuits.

    • Nanditha Rajamani
    • Helen Friedrich
    • Andreas Horn
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • Hollunder et al. identify networks where deep brain stimulation reduces symptoms for Parkinson’s disease, Tourette’s syndrome, dystonia and obsessive-compulsive disorder. This revealed a fronto-rostral topography that segregates the frontal cortex.

    • Barbara Hollunder
    • Jill L. Ostrem
    • Andreas Horn
    ResearchOpen Access
    Nature Neuroscience
    Volume: 27, P: 573-586

  • Deep brain stimulation has been investigated as a potential treatment for cognitive impairments in Alzheimer’s disease. Here the authors carry out post hoc analysis of multi-center cohorts to investigate the anatomical and functional correlates of effective deep brain stimulation, and find that stimulating circuit of Papez, fornix and bed nucleus of the stria terminalis, and a multi-region functional network, were associated with clinical improvement.

    • Ana Sofía Ríos
    • Simón Oxenford
    • Andreas Horn
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14