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Showing 1–3 of 3 results
Advanced filters: Author: Nareg Ohannesian Clear advanced filters

  • Here, the authors report on an imaging method based on localized surface plasmon resonance excitation, employing gold nanodisk arrays as substrates that enable imaging of transparent dielectric particles of several sizes. They demonstrate the ability to detect and image particles smaller than the diffraction limit at 25 nm with standard bright-field imaging.

    • Nareg Ohannesian
    • Ibrahim Misbah
    • Wei-Chuan Shih
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10

  • Ohannesian, Mallick et al. demonstrate label-free counting and detection of microRNA cargoes for single small extracellular vesicles (sEVs), revealing elevated sEV counts and distinct molecular contents in samples from patients with cancer. Using a simple threshold of sEV count in a blind test, classification of cancer vs. healthy samples is achieved with high sensitivity and specificity.

    • Nareg Ohannesian
    • Mohammad Sadman Mallick
    • Wei-Chuan Shih
    ResearchOpen Access
    Communications Medicine
    Volume: 4, P: 1-10