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Showing 1–2 of 2 results
Advanced filters: Author: Narendra Kumar Chunduri Clear advanced filters

  • In this Review Article, Chunduri and Storchová discuss how aneuploidy, often seen in cancer cells, affects gene expression, proliferation, proteotoxic stress and genomic stability, and how these changes relate to those in cancer.

    • Narendra Kumar Chunduri
    • Zuzana Storchová
    Reviews
    Nature Cell Biology
    Volume: 21, P: 54-62

  • The mechanisms that allow cancer cells to survive with monosomies are poorly understood. Here the authors analyse p53-deficient monosomic cell lines using transcriptomics and proteomics, and find that impaired ribosome biogenesis and p53 downregulation are associated with sustained monosomies.

    • Narendra Kumar Chunduri
    • Paul Menges
    • Zuzana Storchova
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17