Preclinical studies have shown that negative pressure ventilation ex situ lung perfusion results in less ventilator-induced lung injury compared to positive pressure ventilation of donor lungs during transplantation procedures. Here the authors perform a single-arm clinical trial with 12 participants to study patient survival and primary graft dysfunction with ex situ lung perfusion.
- Max T. Buchko
- Nasim Boroumand
- Jayan Nagendran
