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Showing 1–2 of 2 results
Advanced filters: Author: Natalie Barretto Clear advanced filters

  • Transcriptome and functional studies in human iPSC-derived neurons suggest that the phenotypic effects of NRXN1 deletions can occur through reduction in wild-type NRXN1α isoform levels and expression of mutant NRXN1α isoforms.

    • Erin Flaherty
    • Shijia Zhu
    • Kristen J. Brennand
    Research
    Nature Genetics
    Volume: 51, P: 1679-1690

  • Combinatorial perturbation of schizophrenia risk loci in human induced pluripotent stem cell–derived neuronal cells demonstrates a synergistic effect converging on synaptic function.

    • Nadine Schrode
    • Seok-Man Ho
    • Kristen J. Brennand
    Research
    Nature Genetics
    Volume: 51, P: 1475-1485