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Showing 1–8 of 8 results
Advanced filters: Author: Nataliya Petryk Clear advanced filters

  • For Okazaki fragments to efficiently mature, RNA primers need to be removed. A recent study in Nature Structural & Molecular Biology implicates ADAR1 in editing mismatched primers to promote unabated lagging-strand synthesis, via oxidation-dependent dimerization and activation of ADAR1.

    • Nataliya Petryk
    News & Views
    Nature Structural & Molecular Biology
    P: 1-2

  • A 2017 cryo-electron microscopy structure that resolved the orientation of the replicative helicase CMG at the DNA replication fork caused a major shift in our understanding of DNA replication.

    • Nataliya Petryk
    Research Highlights
    Nature Reviews Molecular Cell Biology
    Volume: 26, P: 908

  • The physical origin and termination sites of DNA replication in human cells have remained elusive. Here the authors use Okazaki fragment sequencing to reveal global replication patterns and show how chromatin and transcription modulate the process.

    • Nataliya Petryk
    • Malik Kahli
    • Olivier Hyrien
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-13

  • The authors describe procedures for genome-wide quantification of histone modifications and chromatin-associated proteins after replication (chromatin occupancy after replication-seq) and for profiling their relative occupancy in nascent sister chromatids (sister chromatids after replication-seq).

    • Nataliya Petryk
    • Nazaret Reverón-Gómez
    • Anja Groth
    Protocols
    Nature Protocols
    Volume: 16, P: 4446-4493

  • Groth and colleagues discuss recent advances in chromatin replication and maintenance across mitotic division, with emphasis on replication-coupled chromatin assembly and chromatin maturation post-replication.

    • Kathleen R. Stewart-Morgan
    • Nataliya Petryk
    • Anja Groth
    Reviews
    Nature Cell Biology
    Volume: 22, P: 361-371